European Neuropsychopharmacology
Volume 20, Issue 8 , Pages 519-534 , August 2010

Exploring the brain network: A review on resting-state fMRI functional connectivity

  • Martijn P. van den Heuvel

      Affiliations

    • Corresponding Author InformationCorresponding author. Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Heidelberglaan 100, 3508 GA Utrecht, PO BOX 85500, The Netherlands. Tel.: +31 88 75 58244; fax: +31 88 75 55443.
  • ,
  • Hilleke E. Hulshoff Pol

Received 16 December 2009 ,Revised 22 March 2010 ,Accepted 23 March 2010.

References 

  1. Achard S, Bullmore E. Efficiency and cost of economical brain functional networks. PLoS Comput. Biol. 2007;3(2):e17
  2. Achard S, Salvador R, Whitcher B, Suckling J, Bullmore E. A resilient, low-frequency, small-world human brain functional network with highly connected association cortical hubs. J. Neurosci. 2006;26(1):63–72
  3. Aertsen AM, Gerstein GL, Habib MK, Palm G. Dynamics of neuronal firing correlation: modulation of “effective connectivity”. J. Neurophysiol. 1989;61(5):900–917
  4. Andreasen NC, Paradiso S, O'Leary DS. “Cognitive dysmetria” as an integrative theory of schizophrenia: a dysfunction in cortical–subcortical–cerebellar circuitry?. Schizophr. Bull. 1998;24(2):203–218
  5. Andrews-Hanna JR, Snyder AZ, Vincent JL, Lustig C, Head D, Raichle ME, et al. Disruption of large-scale brain systems in advanced aging. Neuron. 2007;56(5):924–935
  6. Barabasi AL, Albert R. Emergence of scaling in random networks. Science. 1999;286(5439):509–512
  7. Barabasi AL, Bonabeau E. Scale-free networks. Sci. Am. 2003;288(5):60–69
  8. Bassett DS, Meyer-Lindenberg A, Achard S, Duke T, Bullmore E. Adaptive reconfiguration of fractal small-world human brain functional networks. Proc. Natl. Acad. Sci. U. S. A. 2006;103(51):19,518–19,523
  9. Bassett DS, Bullmore E, Verchinski BA, Mattay VS, Weinberger DR, Meyer-Lindenberg A. Hierarchical organization of human cortical networks in health and schizophrenia. J. Neurosci. 2008;28(37):9239–9248
  10. Beckmann CF, DeLuca M, Devlin JT, Smith SM. Investigations into resting-state connectivity using independent component analysis. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 2005;360(1457):1001–1013
  11. Birn RM, Diamond JB, Smith MA, Bandettini PA. Separating respiratory-variation-related fluctuations from neuronal-activity-related fluctuations in fMRI. Neuroimage. 2006;31(4):1536–1548
  12. Birn RM, Smith MA, Jones TB, Bandettini PA. The respiration response function: the temporal dynamics of fMRI signal fluctuations related to changes in respiration. Neuroimage. 2008;40(2):644–654
  13. Biswal B, Yetkin FZ, Haughton VM, Hyde JS. Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn. Reson. Med. 1995;34(4):537–541
  14. Biswal BB, Van Kylen J, Hyde JS. Simultaneous assessment of flow and BOLD signals in resting-state functional connectivity maps. NMR Biomed. 1997;10(4–5):165–170
  15. Bleuler . Dementia Praecox or the Group of Schizophrenias. New York: International Universities Press; 1911;
  16. Bluhm RL, Miller J, Lanius RA, Osuch EA, Boksman K, Neufeld R, et al. Spontaneous low-frequency fluctuations in the BOLD signal in schizophrenic patients: anomalies in the default network. Schizophr. Bull. 2007;33:1004–1012
  17. Buckner RL, Vincent JL. Unrest at rest: default activity and spontaneous network correlations. Neuroimage. 2007;37(4):1091–1096
  18. Buckner RL, Andrews-Hanna JR, Schacter DL. The brain's default network: anatomy, function, and relevance to disease. Ann. N. Y. Acad. Sci. 2008;1124:1–38
  19. Buckner RL, Sepulcre J, Talukdar T, Krienen FM, Liu H, Hedden T, et al. Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease. J. Neurosci. 2009;29(6):1860–1873
  20. Bullmore E, Sporns O. Complex brain networks: graph theoretical analysis of structural and functional systems. Nat. Rev. Neurosci. 2009;10(3):186–198
  21. Buzsaki G, Draguhn A. Neuronal oscillations in cortical networks. Science. 2004;304(5679):1926–1929
  22. Calhoun VD, Adali T, Pearlson GD, Pekar JJ. A method for making group inferences from functional MRI data using independent component analysis. Hum. Brain Mapp. 2001;14(3):140–151
  23. Chang C, Cunningham JP, Glover GH. Influence of heart rate on the BOLD signal: the cardiac response function. Neuroimage. 2009;44(3):857–869
  24. Chen BL, Hall DH, Chklovskii DB. Wiring optimization can relate neuronal structure and function. Proc. Natl. Acad. Sci. U. S. A. 2006;103(12):4723–4728
  25. Chiang MC, Barysheva M, Shattuck DW, Lee AD, Madsen SK, Avedissian C, et al Genetics of brain fiber architecture and intellectual performance. J. Neurosci. 2009;29(7):2212–2224
  26. Cordes D, Haughton VM, Arfanakis K, Wendt GJ, Turski PA, Moritz CH, et al. Mapping functionally related regions of brain with functional connectivity MR imaging. AJNR Am. J. Neuroradiol. 2000;21(9):1636–1644
  27. Cordes D, Haughton VM, Arfanakis K, Carew JD, Turski PA, Moritz CH, et al. Frequencies contributing to functional connectivity in the cerebral cortex in “resting-state” data. AJNR Am. J. Neuroradiol. 2001;22(7):1326–1333
  28. Cordes D, Haughton V, Carew JD, Arfanakis K, Maravilla K. Hierarchical clustering to measure connectivity in fMRI resting-state data. Magn. Reson. Imaging. 2002;20(4):305–317
  29. Damoiseaux JS, Greicius MD. Greater than the sum of its parts: a review of studies combining structural connectivity and resting-state functional connectivity. Brain Struct. Funct. 2009;213(6):525–533(Epub 2009 Jun 30)
  30. Damoiseaux JS, Rombouts SA, Barkhof F, Scheltens P, Stam CJ, Smith SM, et al. Consistent resting-state networks across healthy subjects. Proc. Natl. Acad. Sci. U. S. A. 2006;103(37):13,848–13,853
  31. Damoiseaux JS, Beckmann CF, Arigita EJ, Barkhof F, Scheltens P, Stam CJ, et al. Reduced resting-state brain activity in the “default network” in normal aging. Cereb. Cortex. 2007;18(8):1856–1864(Epub 2007 Dec 5)
  32. de Haan W, Stam CJ, Jones BF, Zuiderwijk IM, van Dijk BW, Scheltens P. Resting-state oscillatory brain dynamics in Alzheimer disease. J. Clin. Neurophysiol. 2008;25(4):187–193
  33. De Luca M, Smith S, De Stefano N, Federico A, Matthews PM. Blood oxygenation level dependent contrast resting state networks are relevant to functional activity in the neocortical sensorimotor system. Exp. Brain Res. 2005;167(4):587–594
  34. De Luca M, Beckmann CF, De Stefano N, Matthews PM, Smith SM. fMRI resting state networks define distinct modes of long-distance interactions in the human brain. Neuroimage. 2006;29(4):1359–1367
  35. Eguiluz VM, Chialvo DR, Cecchi GA, Baliki M, Apkarian AV. Scale-free brain functional networks. Phys. Rev. Lett. 2005;94(1):018102
  36. Fox MD, Raichle ME. Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat. Rev. Neurosci. 2007;8(9):700–711
  37. Fox MD, Snyder AZ, Vincent JL, Corbetta M, Van Essen DC, Raichle ME. The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proc. Natl. Acad. Sci. U. S. A. 2005;102(27):9673–9678
  38. Fraiman D, Balenzuela P, Foss J, Chialvo DR. Ising-like dynamics in large-scale functional brain networks. Phys. Rev. E Stat. Nonlin. Soft Matter. Phys. 2009;79(6 Pt 1):061922
  39. Fransson P. Spontaneous low-frequency BOLD signal fluctuations: an fMRI investigation of the resting-state default mode of brain function hypothesis. Hum. Brain Mapp. 2005;26(1):15–29
  40. Friston KJ. The disconnection hypothesis. Schizophr. Res. 1998;30(2):115–125
  41. Friston KJ, Frith CD. Schizophrenia: a disconnection syndrome?. Clin. Neurosci. 1995;3(2):89–97
  42. Friston KJ, Frith CD, Liddle PF, Frackowiak RS. Functional connectivity: the principal-component analysis of large (PET) data sets. J. Cereb. Blood Flow Metab. 1993;13(1):5–14
  43. Garrity AG, Pearlson GD, McKiernan K, Lloyd D, Kiehl KA, Calhoun VD. Aberrant “default mode” functional connectivity in schizophrenia. Am. J. Psychiatry. 2007;164(3):450–457
  44. Greicius M. Resting-state functional connectivity in neuropsychiatric disorders. Curr. Opin. Neurol. 2008;21(4):424–430
  45. Greicius MD, Krasnow B, Reiss AL, Menon V. Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc. Natl. Acad. Sci. U. S. A. 2003;100(1):253–258
  46. Greicius MD, Srivastava G, Reiss AL, Menon V. Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc. Natl. Acad. Sci. U. S. A. 2004;101(13):4637–4642
  47. Greicius MD, Flores BH, Menon V, Glover GH, Solvason HB, Kenna H, et al. Resting-state functional connectivity in major depression: abnormally increased contributions from subgenual cingulate cortex and thalamus. Biol. Psychiatry. 2007;62:429–437
  48. Greicius MD, Supekar K, Menon V, Dougherty RF. Resting-state functional connectivity reflects structural connectivity in the default mode network. Cereb. Cortex. 2008;19(1):72–78(Epub 2008 Apr 9)
  49. Grigorov MG. Global properties of biological networks. Drug Discov. Today. 2005;10(5):365–372
  50. Gusnard DA, Raichle ME, Raichle ME. Searching for a baseline: functional imaging and the resting human brain. Nat. Rev. Neurosci. 2001;2(10):685–694
  51. Hagmann P, Cammoun L, Gigandet X, Meuli R, Honey CJ, Wedeen VJ, et al. Mapping the structural core of human cerebral cortex. PLoS Biol. 2008;6(7):e159
  52. Harrison BJ, Yucel M, Pujol J, Pantelis C. Task-induced deactivation of midline cortical regions in schizophrenia assessed with fMRI. Schizophr. Res. 2007;91(1–3):82–86(Epub 2007 Feb 16)
  53. Honey CJ, Kotter R, Breakspear M, Sporns O. Network structure of cerebral cortex shapes functional connectivity on multiple time scales. Proc. Natl. Acad. Sci. U. S. A. 2007;104(24):10,240–10,245
  54. Honey CJ, Sporns O, Cammoun L, Gigandet X, Thiran JP, Meuli R, et al. Predicting human resting-state functional connectivity from structural connectivity. Proc. Natl. Acad. Sci. U. S. A. 2009;106(6):2035–2040
  55. Hulshoff Pol HE, Schnack HG, Mandl RC, van Haren NE, Koning H, Collins DL, et al. Focal gray matter density changes in schizophrenia. Arch. Gen. Psychiatry. 2001;58(12):1118–1125
  56. Hulshoff Pol HE, Schnack HG, Mandl RC, Cahn W, Collins DL, Evans AC, et al. Focal white matter density changes in schizophrenia: reduced inter-hemispheric connectivity. Neuroimage. 2004;21(1):27–35
  57. Jiang T, He Y, Zang Y, Weng X. Modulation of functional connectivity during the resting state and the motor task. Hum. Brain Mapp. 2004;22(1):63–71
  58. Jung RE, Haier RJ. The Parieto-Frontal Integration Theory (P-FIT) of intelligence: converging neuroimaging evidence. Behav. Brain Sci. 2007;30(2):135–154Discussion 154-87
  59. Kaiser M, Hilgetag CC. Nonoptimal component placement, but short processing paths, due to long-distance projections in neural systems. PLoS Comput. Biol. 2006;2(7):e95
  60. Kim JJ, Kwon JS, Park HJ, Youn T, Kang DH, Kim MS, et al. Functional disconnection between the prefrontal and parietal cortices during working memory processing in schizophrenia: a [15(O)]H2O PET study. Am. J. Psychiatry. 2003;160(5):919–923
  61. Kim JJ, Ho Seok J, Park HJ, Soo Lee D, Chul Lee M, Kwon JS. Functional disconnection of the semantic networks in schizophrenia. Neuroreport. 2005;16(4):355–359
  62. Koch MA, Norris DG, Hund-Georgiadis M. An investigation of functional and anatomical connectivity using magnetic resonance imaging. Neuroimage. 2002;16(1):241–250
  63. Kraepelin . Dementia Praecox and Paraphrenia. Edinburgh: Livingstone; 1919;
  64. Kubicki M, McCarley RW, Shenton ME. Evidence for white matter abnormalities in schizophrenia. Curr. Opin. Psychiatry. 2005;18(2):121–134
  65. Kubicki M, McCarley R, Westin CF, Park HJ, Maier S, Kikinis R, et al. A review of diffusion tensor imaging studies in schizophrenia. J. Psychiatr Res. 2007;41(1–2):15–30
  66. Larson-Prior LJ, Zempel JM, Nolan TS, Prior FW, Snyder AZ, Raichle ME. Cortical network functional connectivity in the descent to sleep. Proc. Natl. Acad. Sci. U. S. A. 2009;106(11):4489–4494
  67. Latora V, Marchiori M. Efficient behavior of small-world networks. Phys. Rev. Lett. 2001;87(19):198,701
  68. Lawes IN, Barrick TR, Murugam V, Spierings N, Evans DR, Song M, et al. Atlas-based segmentation of white matter tracts of the human brain using diffusion tensor tractography and comparison with classical dissection. Neuroimage. 2008;39(1):62–79
  69. Li Y, Liu Y, Li J, Qin W, Li K, Yu C, et al. Brain anatomical network and intelligence. PLoS Comput. Biol. 2009;5(5):e1000395
  70. Liang M, Zhou Y, Jiang T, Liu Z, Tian L, Liu H, et al. Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging. Neuroreport. 2006;17(2):209–213
  71. Liu Y, Liang M, Zhou Y, He Y, Hao Y, Song M, et al. Disrupted small-world networks in schizophrenia. Brain. 2008;131(4):945
  72. Lowe MJ, Mock BJ, Sorenson JA. Resting state fMRI signal correlations in multi-slice EPI. Neuroimage. 1996;3(S257):
  73. Lowe MJ, Mock BJ, Sorenson JA. Functional connectivity in single and multislice echoplanar imaging using resting-state fluctuations. Neuroimage. 1998;7(2):119–132
  74. Lowe MJ, Dzemidzic M, Lurito JT, Mathews VP, Phillips MD. Correlations in low-frequency BOLD fluctuations reflect cortico–cortical connections. Neuroimage. 2000;12(5):582–587
  75. Lowe MJ, Beall EB, Sakaie KE, Koenig KA, Stone L, Marrie RA, et al. Resting state sensorimotor functional connectivity in multiple sclerosis inversely correlates with transcallosal motor pathway transverse diffusivity. Hum. Brain Mapp. 2008;29(7):818–827
  76. Mandl RC, Schnack HG, Luigjes J, van den Heuvel MP, Cahn W, Kahn RS, et al. Tract-based analysis of magnetization transfer ratio and diffusion tensor imaging of the frontal and frontotemporal connections in schizophrenia. Schizophr. Bull. 2008;(2008 November 27, Electronic publication ahead of print)
  77. Mason MF, Norton MI, Van Horn JD, Wegner DM, Grafton ST, Macrae CN. Wandering minds: the default network and stimulus-independent thought. Science. 2007;315(5810):393–395
  78. Mathias N, Gopal V. Small worlds: how and why. Phys. Rev. E Stat. Nonlin. Soft Matter. Phys. 2001;63(2 Pt 1):021117
  79. Micheloyannis S, Pachou E, Stam CJ, Breakspear M, Bitsios P, Vourkas M, et al. Small-world networks and disturbed functional connectivity in schizophrenia. Schizophr. Res. 2006;87(1–3):60–66
  80. Micheloyannis S, Pachou E, Stam CJ, Vourkas M, Erimaki S, Tsirka V. Using graph theoretical analysis of multi channel EEG to evaluate the neural efficiency hypothesis. Neurosci. Lett. 2006;402(3):273–277
  81. Mohammadi B, Kollewe K, Samii A, Krampfl K, Dengler R, Munte TF. Changes of resting state brain networks in amyotrophic lateral sclerosis. Exp. Neurol. 2009;217(1):147–153
  82. Nestor PG, Kubicki M, Spencer KM, Niznikiewicz M, McCarley RW, Shenton ME. Attentional networks and cingulum bundle in chronic schizophrenia. Schizophr. Res. 2007;90(1–3):308–315
  83. Neubauer AC, Fink A. Intelligence and neural efficiency. Neurosci. Biobehav. Rev. 2009;33(7):1004–1023
  84. Nir Y, Mukamel R, Dinstein I, Privman E, Harel M, Fisch L, et al Interhemispheric correlations of slow spontaneous neuronal fluctuations revealed in human sensory cortex. Nat. Neurosci. 2008;11(9):8
  85. Raichle ME, Snyder AZ. A default mode of brain function: a brief history of an evolving idea. Neuroimage. 2007;37(4):1083–1090
  86. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL. A default mode of brain function. Proc. Natl. Acad. Sci. U. S. A. 2001;98(2):676–682
  87. Reijneveld JC, Ponten SC, Berendse HW, Stam CJ. The application of graph theoretical analysis to complex networks in the brain. Clin. Neurophysiol. 2007;118:2317–2331
  88. Rombouts SA, Barkhof F, Goekoop R, Stam CJ, Scheltens P. Altered resting state networks in mild cognitive impairment and mild Alzheimer's disease: an fMRI study. Hum. Brain Mapp. 2005;26(4):231–239
  89. Rombouts SA, Damoiseaux JS, Goekoop R, Barkhof F, Scheltens P, Smith SM, et al. Model-free group analysis shows altered BOLD FMRI networks in dementia. Hum. Brain Mapp. 2009;30(1):256–266
  90. Rubinov M, Sporns O. Complex network measures of brain connectivity: uses and interpretations. Neuroimage. 2009;(2009 October 9, Electronic publication ahead of print)
  91. Salvador R, Suckling J, Coleman MR, Pickard JD, Menon D, Bullmore E. Neurophysiological architecture of functional magnetic resonance images of human brain. Cereb. Cortex. 2005;15(9):1332–1342
  92. Salvador R, Suckling J, Schwarzbauer C, Bullmore E. Undirected graphs of frequency-dependent functional connectivity in whole brain networks. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 2005;360(1457):937–946
  93. Schmahmann JD, Pandya DN, Wang R, Dai G, D'Arceuil HE, de Crespigny AJ, et al. Association fibre pathways of the brain: parallel observations from diffusion spectrum imaging and autoradiography. Brain. 2007;130(Pt 3):630–653
  94. Seeley WW, Crawford RK, Zhou J, Miller BL, Greicius MD. Neurodegenerative diseases target large-scale human brain networks. Neuron. 2009;62(1):42–52
  95. Shmuel A, Leopold DA. Neuronal correlates of spontaneous fluctuations in fMRI signals in monkey visual cortex: implications for functional connectivity at rest. Hum. Brain Mapp. 2008;29(7):751–761
  96. Shmuel A, Yacoub E, Pfeuffer J, Van de Moortele PF, Adriany G, Hu X, et al. Sustained negative BOLD, blood flow and oxygen consumption response and its coupling to the positive response in the human brain. Neuron. 2002;36(6):1195–1210
  97. Shmueli K, van Gelderen P, de Zwart JA, Horovitz SG, Fukunaga M, Jansma JM, et al. Low-frequency fluctuations in the cardiac rate as a source of variance in the resting-state fMRI BOLD signal. Neuroimage. 2007;38(2):306–320
  98. Song M, Zhou Y, Li J, Liu Y, Tian L, Yu C, et al. Brain spontaneous functional connectivity and intelligence. Neuroimage. 2008;41(3):1168–1176
  99. Sporns O, Chialvo DR, Kaiser M, Hilgetag CC. Organization, development and function of complex brain networks. Trends Cogn. Sci. 2004;8(9):418–425
  100. Stam CJ. Functional connectivity patterns of human magnetoencephalographic recordings: a ‘small-world’ network?. Neurosci. Lett. 2004;355(1–2):25–28
  101. Stam CJ, Reijneveld JC. Graph theoretical analysis of complex networks in the brain. Nonlinear Biomed. Phys. 2007;1(1):3
  102. Stam CJ, de Haan W, Daffertshofer A, Jones BF, Manshanden I, van Cappellen van Walsum AM, et al Graph theoretical analysis of magnetoencephalographic functional connectivity in Alzheimer's disease. Brain. 2009;132(Pt 1):213–224
  103. Sun Z, Wang F, Cui L, Breeze J, Du X, Wang X, et al Abnormal anterior cingulum in patients with schizophrenia: a diffusion tensor imaging study. Neuroreport. 2003;14(14):1833–1836
  104. Supekar K, Menon V, Rubin D, Musen M, Greicius MD. Network analysis of intrinsic functional brain connectivity in Alzheimer's disease. PLoS Comput. Biol. 2008;4(6):e1000100
  105. Thirion B, Dodel S, Poline JB. Detection of signal synchronizations in resting-state fMRI datasets. Neuroimage. 2006;29(1):321–327
  106. van Buuren M, Gladwin TE, Zandbelt BB, van den Heuvel M, Ramsey NF, Kahn RS, et al. Cardiorespiratory effects on default-mode network activity as measured with fMRI. Hum. Brain Mapp. 2009;30(9):3031–3042
  107. van de Ven VG, Formisano E, Prvulovic D, Roeder CH, Linden DE. Functional connectivity as revealed by spatial independent component analysis of fMRI measurements during rest. Hum. Brain Mapp. 2004;22(3):165–178
  108. Van den Heuvel MP, Hulshoff Pol HE. Specific somatotopic organization of functional connections of the primary motor network during resting-state. Hum. Brain Mapp. 2010;31(4):631–644
  109. Van den Heuvel MP, Mandl RC, Hulshoff Pol HE. Normalized group clustering of resting-state fMRI data. PLoS ONE. 2008;3(4):e2001
  110. Van den Heuvel MP, Mandl RC, Luigjes J, Hulshoff Pol HE. Microstructural organization of the cingulum tract and the level of default mode functional connectivity. J. Neurosci. 2008;43(28):7
  111. Van den Heuvel MP, Stam CJ, Boersma M, Hulshoff Pol HE. Small-world and scale-free organization of voxel based resting-state functional connectivity in the human brain. Neuroimage. 2008;43(3):11
  112. van den Heuvel MP, Stam CJ, Kahn RS, Hulshoff Pol HE. Efficiency of functional brain networks and intellectual performance. J. Neurosci. 2009;29(23):7619–7624
  113. Van den Heuvel MP, Mandl RCW, Kahn RS, Hulshoff Pol HE. Functionally linked resting state networks reflect the underlying structural connectivity architecture of the human brain. Hum. Brain Mapp. 2009;30(10):3127–3141
  114. van Haren NE, Hulshoff Pol HE, Schnack HG, Cahn W, Mandl RC, Collins DL, et al. Focal gray matter changes in schizophrenia across the course of the illness: a 5-year follow-up study. Neuropsychopharmacology. 2007;32(10):2057–2066
  115. Wakana S, Jiang H, Nagae-Poetscher LM, van Zijl PC, Mori S. Fiber tract-based atlas of human white matter anatomy. Radiology. 2004;230(1):77–87
  116. Watts DJ, Strogatz SH. Collective dynamics of ‘small-world’ networks. Nature. 1998;393(6684):440–442
  117. Weissenbacher A, Kasess C, Gerstl F, Lanzenberger R, Moser E, Windischberger C. Correlations and anticorrelations in resting-state functional connectivity MRI: a quantitative comparison of preprocessing strategies. Neuroimage. 2009;47(4):1408–1416
  118. Whitfield-Gabrieli S, Thermenos HW, Milanovic S, Tsuang MT, Faraone SV, McCarley RW, et al Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia. Proc. Natl. Acad. Sci. U. S. A. 2009;106(4):1279–1284
  119. Wise RG, Ide K, Poulin MJ, Tracey I. Resting fluctuations in arterial carbon dioxide induce significant low frequency variations in BOLD signal. Neuroimage. 2004;21(4):1652–1664
  120. Worsley KJ, Chen JI, Lerch J, Evans AC. Comparing functional connectivity via thresholding correlations and singular value decomposition. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 2005;360(1457):913–920
  121. Xiong J, Parsons LM, Gao JH, Fox PT. Interregional connectivity to primary motor cortex revealed using MRI resting state images. Hum. Brain Mapp. 1999;8(2–3):151–156
  122. Xiong J, Ma L, Wang B, Narayana S, Duff EP, Egan GF, et al. Long-term motor training induced changes in regional cerebral blood flow in both task and resting states. Neuroimage. 2008;45(1):75–82
  123. Zhou Y, Liang M, Jiang T, Tian L, Liu Y, Liu Z, et al. Functional dysconnectivity of the dorsolateral prefrontal cortex in first-episode schizophrenia using resting-state fMRI. Neurosci. Lett. 2007;417(3):297–302
  124. Zhou Y, Liang M, Tian L, Wang K, Hao Y, Liu H, et al. Functional disintegration in paranoid schizophrenia using resting-state fMRI. Schizophr. Res. 2007;97(1–3):194–205

PII: S0924-977X(10)00068-4

doi: 10.1016/j.euroneuro.2010.03.008

European Neuropsychopharmacology
Volume 20, Issue 8 , Pages 519-534 , August 2010