European Neuropsychopharmacology
Volume 20, Issue 7 , Pages 459-466 , July 2010

The change of prefrontal QEEG theta cordance as a predictor of response to bupropion treatment in patients who had failed to respond to previous antidepressant treatments

  • Martin Bares

      Affiliations

    • Prague Psychiatric Center, Ustavni 91, Prague 8-Bohnice, 181 03, Czech Republic
    • The Department of Psychiatry and Medical Psychology, 3rd Faculty of Medicine, Charles University, Ruska 87, Prague 10, 100 00, Czech Republic
    • Corresponding Author InformationCorresponding author. Prague Psychiatric Center, Ustavni 91, Prague 8-Bohnice, 181 03, Czech Republic. Tel.: +420 266003330; fax: +420 266003337.
    • ,
  • Martin Brunovsky

      Affiliations

    • Prague Psychiatric Center, Ustavni 91, Prague 8-Bohnice, 181 03, Czech Republic
    • The Department of Psychiatry and Medical Psychology, 3rd Faculty of Medicine, Charles University, Ruska 87, Prague 10, 100 00, Czech Republic
    • The Department of Neurology, Faculty Hospital Na Bulovce, Prague 8, 180 81, Czech Republic
    • ,
  • Tomas Novak

      Affiliations

    • Prague Psychiatric Center, Ustavni 91, Prague 8-Bohnice, 181 03, Czech Republic
    • The Department of Psychiatry and Medical Psychology, 3rd Faculty of Medicine, Charles University, Ruska 87, Prague 10, 100 00, Czech Republic
    • ,
  • Miloslav Kopecek

      Affiliations

    • Prague Psychiatric Center, Ustavni 91, Prague 8-Bohnice, 181 03, Czech Republic
    • The Department of Psychiatry and Medical Psychology, 3rd Faculty of Medicine, Charles University, Ruska 87, Prague 10, 100 00, Czech Republic
    • ,
  • Pavla Stopkova

      Affiliations

    • Prague Psychiatric Center, Ustavni 91, Prague 8-Bohnice, 181 03, Czech Republic
    • The Department of Psychiatry and Medical Psychology, 3rd Faculty of Medicine, Charles University, Ruska 87, Prague 10, 100 00, Czech Republic
    • ,
  • Peter Sos

      Affiliations

    • Prague Psychiatric Center, Ustavni 91, Prague 8-Bohnice, 181 03, Czech Republic
    • The Department of Psychiatry and Medical Psychology, 3rd Faculty of Medicine, Charles University, Ruska 87, Prague 10, 100 00, Czech Republic
    • ,
  • Vladimir Krajca

      Affiliations

    • The Department of Neurology, Faculty Hospital Na Bulovce, Prague 8, 180 81, Czech Republic
    • Faculty of Biomedical Engineering, Czech Technical University in Prague, nam. Sitna 3105, Kladno, 272 01, Czech Republic
    • ,
  • Cyril Höschl

      Affiliations

    • Prague Psychiatric Center, Ustavni 91, Prague 8-Bohnice, 181 03, Czech Republic
    • The Department of Psychiatry and Medical Psychology, 3rd Faculty of Medicine, Charles University, Ruska 87, Prague 10, 100 00, Czech Republic

Received 21 October 2009 ,Revised 10 February 2010 ,Accepted 14 March 2010.

References 

  1. American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders. 4th ed.. Washington DC: American Psychiatric Press; 1994;
  2. Asada H, Fukuda Y, Tsunoda S, Yamaguchi M, Tonoike M. Frontal midline theta rhythms reflect alternative activation of prefrontal cortex and anterior cingulate cortex in humans. Neurosci. Lett. 1999;274:29–32
  3. Bares M, Brunovsky M, Kopecek M, Stopkova P, Novak T, Kozeny J, et al. Changes in QEEG prefrontal cordance as a predictor of response to antidepressants in patients with treatment resistant depressive disorder: a pilot study. J. Psychiatr. Res. 2007;41:319–325
  4. Bares M, Brunovsky M, Kopecek M, Novak T, Stopkova P, Kozeny J, et al. Early reduction in prefrontal theta QEEG cordance value predicts response to venlafaxine treatment in patients with resistant depressive disorder. Eur. Psychiatry. 2008;23:350–355
  5. Bazire S. Psychotropic Drug Directory 2003/04. The Professionals' Pocket Handbook & Aide Memoire. Salisbury: Five Pin Publishing Limited; 2003;
  6. Beck AT, Rial WY, Rickels K. Short form of depression inventory: cross-validation. Psychol. Rep. 1974;34:1184–1186
  7. Cohen J. Statistical Power Analyses for the Behavioral Sciences. 2nd ed.. Hillsdale: Lawrence Earlbaum Association; 1988;
  8. Cook IA. Biomarkers in psychiatry: potentials, pitfalls, and pragmatics. Primary Psychiatry. 2008;15:54–59
  9. Cook IA, Leuchter AF. Prefrontal changes and treatment response prediction in depression. Semin. Clin. Neuropsychiatry. 2001;6:113–120
  10. Cook IA, O'Hara R, Uijtdehaage SH, Mandelkern M, Leuchter AF. Assessing the accuracy of topographic EEG mapping for determining local brain function. Electroencephalogr. Clin. Neurophysiol. 1998;107:408–414
  11. Cook IA, Leuchter AF, Morgan M, Witte E, Stubbeman WF, Abrams M, et al. Early changes in prefrontal activity characterize clinical responders to antidepressants. Neuropsychopharmacology. 2002;27:120–131
  12. Cook IA, Leuchter AF, Morgan ML, Stubbeman W, Siegman B, Abrams M. Changes in prefrontal activity characterize clinical response in SSRI nonresponders: a pilot study. J. Psychiatr. Res. 2005;39:461–466
  13. Drevets WC. Functional neuroimaging studies of depression: the anatomy of melancholia. Annu. Rev. Med. 1998;49:341–361
  14. Drevets WC, Price JL, Furey ML. Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression. Brain Struct. Funct. 2008;213:93–118
  15. Guy W. ECDEU assessment manual for psychopharmacology— revised. In: US Dept. Health, Education and Welfare Publication (ADM) 76-338. Rockville, MD: National Institute of Mental Health; 1976;p. 218–222
  16. Fredman SJ, Fava M, Kienke AS, White CN, Nierenberg AA, Rosenbaum JF. Partial response, nonresponse, and relapse with selective serotonin reuptake inhibitors in major depression: a survey of current “next-step” practices. J. Clin. Psychiatry. 2000;61:403–408
  17. Hjorth B. An on-line transformation of EEG scalp potentials into orthogonal source derivations. Electroencephalogr. Clin. Neurophysiol. 1975;39:526–530
  18. Hunter AM, Cook IA, Leuchter AF. The promise of the quantitative electroencephalogram as a predictor of antidepressant treatment outcomes in major depressive disorder. Psychiatr. Clin North. Am. 2007;30:105–124
  19. Keller MB. Issues in treatment-resistant depression. J. Clin. Psychiatry. 2005;66(Suppl 8):5–12
  20. Kennedy SH, Fulton KA, Bagby RM, Greene AL, Cohen NL, Rafi-Tar S. Sexual function during bupropion or paroxetine treatment of major depressive disorder. Can. J. Psychiatry. 2006;51:234–242
  21. Kornstein SG, Sloan DME. Depression and gender. In:  Stein DJ,  Kupfer DJ,  Schatzberg AF editor. Textbook of Mood Disorders. Arlington: American Psychiatric Publishing, Inc.; 2006;p. 687–698
  22. Leuchter AF, Cook IA, Lufkin RB, Dunkin J, Newton TF, Cummings JL, et al. Cordance: a new method for assessment of cerebral perfusion and metabolism using quantitative electroencephalography. Neuroimage. 1994;1:208–219
  23. Leuchter AF, Cook IA, Mena I, Dunkin JJ, Cummings JL, Newton TF, et al. Assessment of cerebral perfusion using quantitative EEG cordance. Psychiatry Res. 1994;55:141–152
  24. Leuchter AF, Cook IA, Witte EA, Morgan M, Abrams M. Changes in brain function of depressed subjects during treatment with placebo. Am. J. Psychiatry. 2002;159:122–129
  25. Leuchter AF, Uijtdehaage SH, Cook IA, O'Hara R, Mandelkern M. Relationship between brain electrical activity and cortical perfusion in normal subjects. Psychiatry Res. 1999;90:125–140
  26. Lozano AM, Mayberg HS, Giacobbe P, Hamani C, Craddock RC, Kennedy SH. Subcallosal cingulate gyrus deep brain stimulation for treatment-resistant depression. Biol. Psychiatry. 2008;64:461–467
  27. Mayberg HS, Brannan SK, Mahurin RK, Jerabek PA, Brickman JS, Tekell JL, et al. Cingulate function in depression: a potential predictor of treatment response. Neuroreport. 1997;8:1057–1061
  28. Mayberg HS, Brannan SK, Tekell JL, Silva JA, Mahurin RK, McGinnis S, et al. Regional metabolic effects of fluoxetine in major depression: serial changes and relationship to clinical response. Biol. Psychiatry. 2000;48:830–843
  29. Mayberg HS, Lozano AM, Voon V, McNeely HE, Seminowicz D, Hamani C, et al. Deep brain stimulation for treatment-resistant depression. Neuron. 2005;45:651–660
  30. Montgomery SA, Asberg M. A new depression scale designed to be sensitive to change. Br. J. Psychiatry. 1979;134:382–389
  31. Morgan ML, Witte EA, Cook IA, Leuchter AF, Abrams M, Siegman B. Influence of age, gender, health status, and depression on quantitative EEG. Neuropsychobiology. 2005;52:71–76
  32. Mulert C, Juckel G, Brunnmeier M, Karch S, Leicht G, Mergl R, et al. Rostral anterior cingulate cortex activity in the theta band predicts response to antidepressive medication. Clin. EEG Neurosci. 2007;38:78–81
  33. Nierenberg AA, Farabaugh AH, Alpert JE, Gordon J, Worthington JJ, Rosenbaum JF, et al. Timing of onset of antidepressant response with fluoxetine treatment. Am. J. Psychiatry. 2000;157:1423–1428
  34. Nuwer MR, Lehmann D, da Silva FL, Matsuoka S, Sutherling W, Vibert JF. IFCN guidelines for topographic and frequency analysis of EEGs and EPs. Electroencephalogr. Clin. Neurophysiol. 1999;52:15–20Suppl
  35. Papakostas GI, Kornstein SG, Clayton AH, Soares CN, Hallett LA, Krishen A, et al. Relative antidepressant efficacy of bupropion and the selective serotonin reuptake inhibitors in major depressive disorder: gender–age interactions. Int. Clin. Psychopharmacol. 2007;22:226–229
  36. Papakostas GI, Petersen T, Sklarsky KG, Nierenberg AA, Alpert JE, Fava M. Timing of clinical improvement and symptom resolution in the treatment of major depressive disorder. Psychiatry Res. 2007;149:195–200
  37. Papakostas GI, Fava M, Thase ME. Treatment of SSRI-resistant depression: a meta-analysis comparing within-versus across-class switches. Biol. Psychiatry. 2008;63:699–704
  38. Pizzagalli D, Pascual-Marqui RD, Nitschke JB, Oakes TR, Larson CL, Abercrombie HC, et al. Anterior cingulate activity as a predictor of degree of treatment response in major depression: evidence from brain electrical tomography analysis. Am. J. Psychiatry. 2001;158:405–415
  39. Pizzagalli DA, Oakes TR, Davidson RJ. Coupling of theta activity and glucose metabolism in the human rostral anterior cingulate cortex: an EEG/PET study of normal and depressed subjects. Psychophysiology. 2003;40:939–949
  40. Quitkin FM, Petkova E, McGrath PJ, Tailor B, Beasley C, Stewart J, et al. When should a trial of fluoxetine for major depression be declared failed?. Am. J. Psychiatry. 2003;160:734–740
  41. Rush AJ, Kraemer HC, Sackeim HA, Fava M, Trivedi MH, Frank E, et al. Report by the ACNP Task Force on response and remission in major depressive disorder. Neuropsychopharmacology. 2006;31:1841–1853
  42. Rush AJ, Trivedi MH, Wisniewski SR, Stewart JW, Nierenberg AA, Thase ME, et al. Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression. N. Engl. J. Med. 2006;354:1231–1242
  43. Sackeim HA. The definition and meaning of treatment-resistant depression. J. Clin. Psychiatry. 2001;62(Suppl 16):10–17
  44. Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, et al. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J. Clin. Psychiatry. 1998;59(Suppl 20):22–33
  45. Souery D, Oswald P, Massat I, Bailer U, Bollen J, Demyttenaere K, et al. Clinical factors associated with treatment resistance in major depressive disorder: results from a European multicenter study. J. Clin. Psychiatry. 2007;68:1062–1070
  46. Szegedi A, Jansen WT, van Willigenburg AP, van der Meulen E, Stassen HH, Thase ME. Early improvement in the first 2weeks as a predictor of treatment outcome in patients with major depressive disorder: a meta-analysis including 6562 patients. J. Clin. Psychiatry. 2009;70:344–353
  47. Thase ME, Rush AJ. When at first you don't succeed: sequential strategies for antidepressant nonresponders. J. Clin. Psychiatry. 1997;58(Suppl 13):23–29
  48. Trivedi MH, Morris DW, Grannemann BD, Mahadi S. Symptom clusters as predictors of late response to antidepressant treatment. J. Clin. Psychiatry. 2005;66:1064–1070
  49. Trivedi MH, Rush AJ, Wisniewski SR, Nierenberg AA, Warden D, Ritz L, et al. Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice. Am. J. Psychiatry. 2006;163:28–40

PII: S0924-977X(10)00067-2

doi: 10.1016/j.euroneuro.2010.03.007

European Neuropsychopharmacology
Volume 20, Issue 7 , Pages 459-466 , July 2010

Article Tools