European Neuropsychopharmacology
Volume 20, Issue 8 , Pages 582-593, August 2010

An in vivo pharmacological evaluation of pardoprunox (SLV308) — A novel combined dopamine D2/D3 receptor partial agonist and 5-HT1A receptor agonist with efficacy in experimental models of Parkinson's disease

  • C.A. Jones

      Affiliations

    • Abbott Pharmaceuticals B.V., Weesp, The Netherlands (formerly Solvay Pharmaceuticals B.V.)
    • These authors contributed equally.
    • Present address: School of Biomedical Sciences, Queen's Medical Centre, University of Nottingham, NG7 2UH, UK.
  • ,
  • L.C. Johnston

      Affiliations

    • Neurodegenerative Diseases Research Centre, School of Biomedical and Health Sciences, King's College London, London SE1 1UL, UK
    • These authors contributed equally.
    • Present address: Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.
  • ,
  • M.J. Jackson

      Affiliations

    • Neurodegenerative Diseases Research Centre, School of Biomedical and Health Sciences, King's College London, London SE1 1UL, UK
  • ,
  • L.A. Smith

      Affiliations

    • Neurodegenerative Diseases Research Centre, School of Biomedical and Health Sciences, King's College London, London SE1 1UL, UK
  • ,
  • G. van Scharrenburg

      Affiliations

    • Abbott Pharmaceuticals B.V., Weesp, The Netherlands (formerly Solvay Pharmaceuticals B.V.)
  • ,
  • S. Rose

      Affiliations

    • Neurodegenerative Diseases Research Centre, School of Biomedical and Health Sciences, King's College London, London SE1 1UL, UK
  • ,
  • P.G. Jenner

      Affiliations

    • Neurodegenerative Diseases Research Centre, School of Biomedical and Health Sciences, King's College London, London SE1 1UL, UK
  • ,
  • A.C. McCreary

      Affiliations

    • Abbott Pharmaceuticals B.V., Weesp, The Netherlands (formerly Solvay Pharmaceuticals B.V.)
    • Corresponding Author InformationCorresponding author. Tel.: +31 294 479 514; fax: +31 294 410 069.

Received 28 September 2009; received in revised form 5 February 2010; accepted 10 March 2010. published online 03 May 2010.

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PII: S0924-977X(10)00061-1

doi:10.1016/j.euroneuro.2010.03.001

European Neuropsychopharmacology
Volume 20, Issue 8 , Pages 582-593, August 2010