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European Neuropsychopharmacology
Volume 20, Issue 7
, Pages 433-453
, July 2010
Antidepressants in healthy subjects: What are the psychotropic/psychological effects?
References
- . Citalopram modulation of neuronal responses to aversive face emotions: a functional MRI study. NeuroReport. 2007;18:1351–1355
- . The SSRI antidepressants: exploring their “other” possible properties. J. Affect. Disord. 1998;49:141–144
- . Escitalopram effects on insula and amygdala BOLD activation during emotional processing. Psychopharmacology (Berl). 2008;196:661–672
- . Early effects of mirtazapine on emotional processing. Psychopharmacology (Berl). 2009;203:685–691
- . A validation of the 7.5% CO2 model of GAD using paroxetine and lorazepam in healthy volunteers. J. Psychopharmacol. 2007;21:42–49
- . SSRI-induced apathy syndrome: a clinical review. J. Psychiatr. Pract. 2004;10:196–199
- . Thinking about Prozac. Nature. 1994;363:1102–1103
- . Neural and genetic correlates of antidepressant response to sleep deprivation: a functional magnetic resonance imaging study of moral valence decision in bipolar depression. Arch. Gen. Psychiatry. 2007;64:179–187
- . Effects of paroxetine on emotional functioning and treatment awareness: a 4-week randomized placebo-controlled study in healthy clinicians. Psychopharma- cology (Berl). 2010;207:619–629
- . Acute 5-HT reuptake blockade potentiates human amygdala reactivity. Neuropsychopharmacology. 2008;33:3221–3225
- . Effect of serotonergic antidepressant therapy on temperament and character scales in patients with chronic tension-type headache. Psychiatry Clin. Neurosci. 2007;61:534–542
- . A single dose of citalopram increases fear recognition in healthy subjects. J. Psychopharmacol. 2007;21:684–690
- . Genetic variation in MAOA modulates ventromedial prefrontal circuitry mediating individual differences in human personality. Mol. Psychiatry. 2008;13:313–324
- . The selective serotonin reuptake inhibitor citalopram increases fear after acute treatment but reduces fear with chronic treatment: a comparison with tianeptine. Biol. Psychiatry. 2004;55:1171–1178
- . Acute treatment with the antidepressants bupropion and sertraline do not influence memory retrieval in man. Eur. Arch. Psychiatry Clin. Neurosci. 2006;256:320–325
- . Neurochemical modulation of response inhibition and probabilistic learning in humans. Science. 2006;311:861–863
- . Serotoninergic regulation of emotional and behavioural control processes. Trends Cogn. Sci. 2008;12:31–40
- . Drug-induced stimulation and suppression of action monitoring in healthy volunteers. Psychopharmacology (Berl). 2004;177:151–160
- . Effects of antipsychotic and antidepressant drugs on action monitoring in healthy volunteers. Brain Res. 2006;1105:122–129
- . The effect of citalopram pretreatment on neuronal responses to neuropsychological tasks in normal volunteers: an FMRI study. Neuropsychopharmacology. 2005;30:1724–1734
- . Comparative investigation of the effect of moclobemide and toloxatone on monoamine oxidase activity and psychometric performance in healthy subjects. Psychopharmacology (Berl). 1992;106 Suppl:S68–S70
- . Catechol O-methyltransferase val158met genotype and neural mechanisms related to affective arousal and regulation. Arch. Gen. Psychiatry. 2006;63:1396–1406
- . Effects of fluvoxamine and dothiepin on psychomotor abilities in healthy volunteers. Pharmacol. Biochem. Behav. 1996;53:265–269
- . Listening to Prozac—correspondence. Nature. 1994;369:178
- . SSRIs do not cause affective blunting in healthy elderly volunteers. Am. J. Geriatr. Psychiatry. 2004;12:323–330
- . Effect of clinical doses of fluoxetine on psychological variables in healthy volunteers. Am. J. Psychiatry. 1998;155:290–292
- . A susceptibility gene for affective disorders and the response of the human amygdala. Arch. Gen. Psychiatry. 2005;62:146–152
- . Serotonin and emotional processing: does it help explain antidepressant drug action?. Neuropharmacology. 2008;55:1023–1028
- . Acute SSRI administration affects the processing of social cues in healthy volunteers. Neuropsychopharmacology. 2003;28:148–152
- . Toward a neuropsychological theory of antidepressant drug action: increase in positive emotional bias after potentiation of norepinephrine activity. Am. J. Psychiatry. 2003;160:990–992
- . Increased positive versus negative affective perception and memory in healthy volunteers following selective serotonin and norepinephrine reuptake inhibition. Am. J. Psychiatry. 2004;161:1256–1263
- . Antidepressant drug treatment modifies the neural processing of nonconscious threat cues. Biol. Psychiatry. 2006;59:816–820
- . Dissociable effects of acute antidepressant drug administration on subjective and emotional processing measures in healthy volunteers. Psychopharmacology (Berl). 2008;199:495–502
- . Plasma amitriptyline level after acute administration, and driving performance in healthy volunteers. Psychiatry Clin. Neurosci. 2008;62:610–616
- . The effects of acute treatment with paroxetine, amitriptyline, and placebo on driving performance and cognitive function in healthy Japanese subjects: a double-blind crossover trial. Hum. Psychopharmacol. 2008;23:399–407
- . No effect of six weeks of treatment with escitalopram on mood in healthy volunteers—irrespective of genotype for the promoter of the serotonin transporter. Psychiatry Res. 2008;161:339–343
- . Selective alteration of personality and social behavior by serotonergic intervention. Am. J. Psychiatry. 1998;155:373–379
- . Listening to Prozac. A psychiatrist explores antidepressant drugs and the remaking of the self. New York: Viking; 1993;
- . The neural mechanism underlying the female advantage in identifying negative emotions: an event-related potential study. Neuroimage. 2008;40:1921–1929
- . Actions and interactions of psychotropic drugs on human performance and mood: single doses of ORG 3770, amitriptyline, and diazepam. Pharmacol. Toxicol. 1989;65:81–88
- . Through the doors of deception?. Nature. 1994;368:369–370
- . Single dose antidepressant administration modulates the neural processing of self-referent personality trait words. Neuroimage. 2007;37:904–911
- . Chronic treatment with clomipramine and mianserin increases the hierarchical position of subdominant rats housed in triads. Behav. Pharmacol. 1992;3:239–247
- . Is antidepressant efficacy revealed by drug-induced changes in rat behaviour exhibited during social interaction?. Neurosci. Biobehav. Rev. 1991;15:539–544
- . Short-term antidepressant treatment and facial processing. Functional magnetic resonance imaging study. Br. J. Psychiatry. 2007;190:531–532
- . The effects of reboxetine on emotional processing in healthy volunteers: an fMRI study. Mol. Psychiatry. 2007;13:1011–1020
- . SSRI effects on pyschomotor performance: assessment of citalopram and escitalopram on normal subjects. Aviat. Space Environ. Med. 2007;78:693–697
- . Placebos, drug effects, and study design: a clinician's guide. Am. J. Psychiatry. 1999;156:829–836
- . A placebo controlled investigation into the effects of paroxetine and mirtazapine on measures related to car driving performance. Hum. Psychopharmacol. 2003;18:261–269
- . Specific serotonergic reuptake inhibition impairs vigilance performance acutely and after subchronic treatment. J. Psychopharmacol. 2005;19:12–20
- . Cognitive performance in elderly subjects after a single dose of befloxatone, a new reversible selective monoamine oxidase A inhibitor. Clin. Pharmacol. Ther. 1998;64:211–222
- . Acute effects of the novel antidepressant venlafaxine on cognitive event-related potentials (P300), eye blink rate and mood in young healthy subjects. Int. Clin. Psychopharmacol. 1993;8:155–166
- . Antidepressant drugs: disturbing and potentially dangerous adverse effects. J. Clin. Psychiatry. 1998;59(Suppl 16):25–30discussion 40-2
- . Effects of sertraline on autonomic and cognitive functions in healthy volunteers. Psychopharmacology (Berl). 2003;168:293–298
- . The effects of moclobemide on autonomic and cognitive functions in healthy volunteers. Pharmacopsychiatry. 2004;37:81–87
- . The effects of venlafaxine on cognitive functions and quantitative EEG in healthy volunteers. Pharmacopsychiatry. 2008;41:146–150
- . Antidepressant-induced jitteriness/anxiety syndrome: systematic review. Br. J. Psychiatry. 2009;194:483–490
- . Emotion recognition deficits in the elderly. Int. J. Neurosci. 2004;114:403–432
- . Effects of dopaminergic and serotonergic manipulation on emotional processing: a pharmacological fMRI study. Neuroimage. 2005;27:991–1001
- . Difference in serotonergic and noradrenergic regulation of human social behaviours. Psychopharmacology (Berl). 2002;159:216–221
- . Serotonergic intervention affects both social dominance and affiliative behaviour. Psychopharmacology (Berl). 2002;161:324–330
- . Reboxetine promotes social bonding in healthy volunteers. J. Psychopharmacol. 2003;17:189–195
- . Noradrenaline might enhance assertive human social behaviours: an investigation in a flatmate relationship. Pharmacopsychiatry. 2006;39:175–179
- . Acute and subchronic effects of nefazodone and imipramine on highway driving, cognitive functions, and daytime sleepiness in healthy adult and elderly subjects. J. Clin. Psychopharmacol. 1995;15:30–40
- . Serotonergic modulation of neuronal responses to behavioural inhibition and reinforcing stimuli: an fMRI study in healthy volunteers. Eur. J. NeuroSci. 2006;23:552–560
- . Effects of befloxatone, a reversible selective monoamine oxidase-A inhibitor, on psychomotor function and memory in healthy subjects. J. Clin. Pharmacol. 1996;36:942–950
- . The role of sedation tests in identifying sedative drug effects in healthy volunteers and their power to dissociate sedative-related impairments from memory dysfunctions. J. Psychopharmacol. 2007;21:579–587
- . Effects of 5
weeks of administration of fluoxetine and dothiepin in normal volunteers on sleep, daytime sedation, psychomotor performance and mood. J. Psychopharmacol. 2002;16:321–331 - . Sustained attention and serotonin: a pharmaco-fMRI study. Hum. Psychopharmacol. 2008;23:221–230
- . Citalopram neuropharmacological challenge in alcohol-dependent patients and controls: pharmacogenetic, endocrine and psychobehavioral results. Pharmacopsychiatry. 2008;41:72–78
- . Selective serotonin reuptake inhibitor use associates with apathy among depressed elderly: a case-control study. Ann. Gen. Psychiatry. 2007;6:7
PII: S0924-977X(09)00260-0
doi: 10.1016/j.euroneuro.2009.11.009
© 2009 Elsevier B.V. All rights reserved.
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European Neuropsychopharmacology
Volume 20, Issue 7
, Pages 433-453
, July 2010
